NOT KNOWN FACTS ABOUT LINK ALTERNATIF NAGA26

Inside the crystal framework on the D273N mutant of NagA, the facet chain of His-143 is 3.0 Å away from the phosphonate oxygen of the mimic of your tetrahedral intermediate (21). This end result implies this group could aid the activation of the carbonyl group from the substrate at the side of an interaction While using the metal ion sure in the